Hello and welcome to the forum. Good to have you here.
I have always had problems with SSRIs. Either they did not work well (not many of these) or they had such horrendous side effects I could not take them. I stayed with each one to determine if the side effects would go away but no luck. However, one thing I noticed was that initially there was some relief. I felt very well for a short period. Then this effect disappeared and the side effects clicked in. All very disappointing. After years of trying and putting up with this horrid state of affairs I was switched to a TCA medication. Fantastic.
I see you have tried a number of different SSRIs. May I ask why you kept changing? I'm guessing you were going through some anxiety and were prescribed an antidepressant. Once that patch went away you were OK for a time before needing antidepressant again. So why not go back to the original AD? If it did the job was there a need to change?
Sorry if I am treading on anyone's toes here. Definitely not intended. It simply surprises me you have had so many different meds for no apparent reason. What is the reason for taking this latest AD?
As I said above, I found some of the ADs OK at the start but then the relief disappeared and the side effects clicked in. My understanding of these ADs is how it affects the serotonin levels in your system. Below is a quote from the Mayo Clinic.
SSRIs ease depression
by increasing levels of serotonin in the brain. Serotonin is one of the
chemical messengers (neurotransmitters) that carry signals between
brain cells. SSRIs block the reabsorption (reuptake) of serotonin in the brain, making more serotonin available.
This is another quote from WebMD. I cannot guarantee the accuracy of these statements although they seem to match what I have been told. Perhaps you can check with your prescribing doctor.
When these brain cells (called neurons) send signals to one
another, they release a little bit of a neurotransmitter so that the
message can be delivered. They then have to take back the
neurotransmitter they released so they can send the next message. This
process of replacing the neurotransmitter is called “reuptake.”
One of my problems was the serotonin was reuptake process did not work well causing the side effects even though I also took another AD, a SNRI to stop the reuptake problem.
Long quotes I know but I think it's important to know how our medication works. I now take a TCA medication.