I have been diagnosed with Depression and medicated accordingly, for 14 years. I had to take early retirement. I and my siblings, who are both free of Depression, have a blood clotting disorder. This was found in 1996 or so and is called Factor V Leiden after the University where it was identified.
My parents and I had the condition twice, meaning when we bleed we clot 70 times faster than 85 to 95% of the population. The condition causes clotting in veins, the low pressure blood return system. My parents self medicated with alcohol, most of their lives.
Clots cause scarring of the vessels, which are muscular. Thus there are small amounts of pain every time blood passes an old clot site. DVTs can result, anywhere in the body. The worst place is in the lungs. The pain may build up and be called Fibromyalgia. "Pain from clotting". Those who are of Aryan descent, especially who came from South Sweden, are most likely to have the clotting disorder. Sicily and Lebanon are also hot spots as the Normans carried it strongly. The clots and scarring may be dissolved by enzymes but it is a long process. As at least 5% of the general population appear to have this condition, we must be careful to address it as a factor in increasing stress hormone levels, as a result of the pain of obstructed veins, the scarring and the poor drainage of important organs, such as the brain and gut, where Serotonin is expected to be found.
For those with long term depression treatment should address the possibility of other disorders!
I wish you all the best! Slow down, we are the best kind of people.